Cafe-au-lait spots and neurofibromas are associated with which condition?

Cafe-au-lait spots and neurofibromas are key features associated with Neurofibromatosis, particularly Neurofibromatosis Type 1 (NF1), also known as Von Recklinghausen's disease. The presence of multiple café-au-lait spots is one of the diagnostic criteria for this condition, and they often appear at an early age. Neurofibromas, which are benign tumors of the peripheral nervous system, also form on or beneath the skin and can occur in individuals with NF1.

While referring to Von Recklinghausen's disease is indeed correct, it is essential to note that this term is often used synonymously with Neurofibromatosis Type 1 in the medical context. Therefore, the association of café-au-lait spots and neurofibromas with this specific condition signifies the importance of recognizing the characteristics of NF1 in clinical diagnosis.

The other conditions listed, such as Sturge-Weber syndrome and Tay-Sach's Disease, are not characterized by café-au-lait spots or neurofibromas, highlighting the uniqueness of the features tied to Neurofibromatosis and its synonyms. Thus, the answer reflects an accurate and relevant association within the context of the question.