What sensitivity should be used to resolve the morphology of a 500uV spike discharge?

The appropriate sensitivity to resolve the morphology of a 500 µV spike discharge is indeed 50 µV/mm. When selecting sensitivity for EEG recordings, the goal is to accurately capture the amplitude and shape of the waves being recorded.

At a sensitivity of 50 µV/mm, a 500 µV spike discharge will be represented prominently on the EEG trace, allowing clear visualization of its morphology. This means that the spike will be easily distinguishable from the background activity and other waveforms, enabling proper interpretation. Higher sensitivity settings (such as 7 µV/mm) would result in overly amplified signals that could distort the morphology due to saturation, making it difficult to discern subtle features. Conversely, lower sensitivity settings (like 250 µV/mm or 500 µV/mm) would compress the amplitude of the spike, risking loss of detail and clarity in the waveform.

Thus, 50 µV/mm strikes the right balance, providing a clear and accurate representation of the spike discharge while maintaining fidelity in the recording.