A facial port-wine stain is characteristic of which condition?

A facial port-wine stain is a key feature associated with Sturge-Weber syndrome. This condition is a neurological disorder characterized by a specific type of birthmark, known as a port-wine stain, on the face, particularly along the distribution of the trigeminal nerve.

Sturge-Weber syndrome is also associated with other neurological components, including leptomeningeal angiomas, leading to seizures and other neurological issues. The presence of the port-wine stain can serve as an external indicator that may prompt further evaluation for associated neurological concerns.

In contrast, other conditions listed may have their own unique characteristics and symptoms, but none are specifically linked to port-wine stains in the same direct way that Sturge-Weber syndrome is. Neurofibromatosis is associated with neurofibromas but does not prominently feature port-wine stains. Angelman syndrome is primarily a genetic disorder affecting the nervous system with distinct behavioral and developmental features, and Klippel-Trenaunay syndrome is a vascular disorder characterized by capillary malformations, but it tends to present with different vascular anomalies rather than specifically with port-wine stains.